First Tests of Gaseous Detectors Made of a Resistive Mesh

We describe here various detectors designs: GEM type, MICROMEGAStype, PPACtype as well as cascaded detectors made of a resistive mesh manufactured from a resistive Kapton foil, (20 microns thick, resistivity a few MOhm per square) by a laser drilling technique. As in any other micropattern detectors the maximum achievable gas gain of these detectors is restricted by the Raether limit, however, the resistive mesh makes them and the front end electronics fully spark protected. This approach could be an alternative or complimentary to the ongoing efforts in developing MICROMEGAS and GEMs with resistive anode readout plates and can be especially beneficial in the case of micropattern detectors combined with a micropixel-type integrated front end electronic

An improved design of spark-protected microstrip gas counters (R-MSGC)

We have developed microstrip gas counters manufactured on standard printed circuit board and having the following features: resistive cathode strips, thin (10 micron) metallic anode strips and electrodes protected against surface discharges by a Coverlay layer at their edges. These features allow the detector to operate at gas gains as high as can be achieve with the best microstrip gas counters manufactured on glass substrates. We believe that after further developments this type of detectors can compete in some applications with other micropattern detectors, for example MICROMEGAS.Comment: Presented at the 7th RD51 Collaboration meeting, CERN, April 201

The use of genes for performance enhancement: doping or therapy?

Recent biotechnological advances have permitted the manipulation of genetic sequences to treat several diseases in a process called gene therapy. However, the advance of gene therapy has opened the door to the possibility of using genetic manipulation (GM) to enhance athletic performance. In such ‘gene doping’, exogenous genetic sequences are inserted into a specific tissue, altering cellular gene activity or leading to the expression of a protein product. The exogenous genes most likely to be utilized for gene doping include erythropoietin (EPO), vascular endothelial growth factor (VEGF), insulin-like growth factor type 1 (IGF-1), myostatin antagonists, and endorphin. However, many other genes could also be used, such as those involved in glucose metabolic pathways. Because gene doping would be very difficult to detect, it is inherently very attractive for those involved in sports who are prepared to cheat. Moreover, the field of gene therapy is constantly and rapidly progressing, and this is likely to generate many new possibilities for gene doping. Thus, as part of the general fight against all forms of doping, it will be necessary to develop and continually improve means of detecting exogenous gene sequences (or their products) in athletes. Nevertheless, some bioethicists have argued for a liberal approach to gene doping

Synchronization in the presence of memory

We study the effect of memory on synchronization of identical chaotic systems driven by common external noises. Our examples show that while in general synchronization transition becomes more difficult to meet when memory range increases, for intermediate ranges the synchronization tendency of systems can be enhanced. Generally the synchronization transition is found to depend on the memory range and the ratio of noise strength to memory amplitude, which indicates on a possibility of optimizing synchronization by memory. We also point out on a close link between dynamics with memory and noise, and recently discovered synchronizing properties of networks with delayed interactions